{"id":4055,"date":"2020-11-27T10:25:18","date_gmt":"2020-11-27T07:25:18","guid":{"rendered":"http:\/\/185.149.103.207\/~adanaseshaber\/haber-koronavirus-tedavisine-yonelik-calisma-sonuclandi-12524.html"},"modified":"2020-11-27T10:25:18","modified_gmt":"2020-11-27T07:25:18","slug":"koronavirus-tedavisine-yonelik-calisma-sonuclandi-12524","status":"publish","type":"post","link":"https:\/\/adanaseshaber.com.tr\/?p=4055","title":{"rendered":"Koronavir\u00fcs Tedavisine Y\u00f6nelik \u00c7al\u0131\u015fma Sonu\u00e7land\u0131"},"content":{"rendered":"<p><span style=\"font-family:tahoma,geneva,sans-serif\"><span style=\"font-size:18px\"><span style=\"color:#000000\">&Ccedil;ukurova &Uuml;niversitesi (&Ccedil;&Uuml;) Fen-Edebiyat Fak&uuml;ltesi Biyoloji B&ouml;l&uuml;m&uuml;, Kilis 7 Aral\u0131k &Uuml;niversitesi Molek&uuml;ler Biyoloji ve Genetik B&ouml;l&uuml;m&uuml;, Afyon Sa\u011fl\u0131k Bilimleri &Uuml;niversitesi Eczac\u0131l\u0131k Fak&uuml;ltesi ve Universidade Federal do Rio Grande do Sul &Uuml;niversitesi Fizikokimya B&ouml;l&uuml;m&uuml; ile i\u015fbirli\u011fi i&ccedil;erisinde y&uuml;r&uuml;t&uuml;len koronavir&uuml;se kar\u015f\u0131 in silico ila&ccedil; tarama &ccedil;al\u0131\u015fmas\u0131 \u0130ngiltere merkezli &quot;Journal of Biomolecular Structure and Dynamics&quot; adl\u0131 bilimsel dergide &quot;In silico analysis of the interactions of certain flavonoids with the receptor-binding domain of 2019 novel corona virus and cellular proteases and their pharmacokinetic properties&quot; adl\u0131 makale ba\u015fl\u0131\u011f\u0131 ile yay\u0131nland\u0131.<\/span><\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-family:tahoma,geneva,sans-serif\"><span style=\"font-size:18px\"><span style=\"color:#000000\"><strong>Koronavir&uuml;s Tedavisine Y&ouml;nelik &Ccedil;al\u0131\u015fma Sonu&ccedil;land\u0131<\/strong><\/span><\/span><\/span><\/p>\n<p><span style=\"font-family:tahoma,geneva,sans-serif\"><span style=\"font-size:18px\"><span style=\"color:#000000\">Biyoinformatik temelli aday ila&ccedil; molek&uuml;l&uuml; tarama &ccedil;al\u0131\u015fmas\u0131 (&Ccedil;&Uuml;) Fen-Edebiyat Fak&uuml;ltesi Biyoloji B&ouml;l&uuml;m&uuml;nden Dr. Erman Salih \u0130stifli, Prof. Dr. Bekta\u015f Tepe ve Prof. Dr. Cengiz Sar\u0131k&uuml;rk&ccedil;&uuml; taraf\u0131ndan koronavir&uuml;s (SARS-CoV-2, 2019-nCoV) tedavisine y&ouml;nelik olarak ba\u015flat\u0131larak, bu s&uuml;re&ccedil; i&ccedil;erisinde Brezilya Universidade Federal do Rio Grande do Sul &Uuml;niversitesi Fizikokimya B&ouml;l&uuml;m&uuml;&#39;nden Prof. Dr. Paulo A. Netz&#39;in de kat\u0131l\u0131m\u0131yla tamamland\u0131.<\/span><\/span><\/span><\/p>\n<p><span style=\"font-family:tahoma,geneva,sans-serif\"><span style=\"font-size:18px\"><span style=\"color:#000000\">Dr. Erman Salih \u0130stifli, &ccedil;al\u0131\u015fmada farkl\u0131 bir yakla\u015f\u0131m takip ederek sadece koronavir&uuml;s&uuml;n spike proteini de\u011fil, ayn\u0131 zamanda konak organizmada (insan) enfeksiyonun ilerlemesinde rol alan cathepsin B, cathepsin L ve TMPRSS2 enzimlerine kar\u015f\u0131 da y&uuml;ksek afinite ile ba\u011flanan aday ila&ccedil; molek&uuml;lleri bulduklar\u0131n\u0131 belirtti.<\/span><\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span style=\"font-family:tahoma,geneva,sans-serif\"><span style=\"font-size:18px\"><span style=\"color:#000000\">B&ouml;ylelikle koronavir&uuml;s enfeksiyonu ile m&uuml;cadelede &ccedil;oklu-hedef yakla\u015f\u0131m\u0131n\u0131n benimsendi\u011fini ifade eden Dr. \u0130stifli, bu &ccedil;al\u0131\u015fman\u0131n &ouml;ne &ccedil;\u0131kan &ouml;zelliklerini &ldquo;SARS-CoV-2 enfeksiyonunda tedavide kullan\u0131labilecek&nbsp;potansiyel ila&ccedil; molek&uuml;llerinin ke\u015ffinde Uluslararas\u0131 i\u015fbirli\u011fi ile ger&ccedil;ekle\u015ftirilmi\u015f olmas\u0131, &Ccedil;ukurova &Uuml;niversitesi Biyoloji B&ouml;l&uuml;m&uuml; ve &Ccedil;ukurova &Uuml;niversitesinin&nbsp;atomik yap\u0131sal biyoloji,&nbsp;biyolojik molek&uuml;llerin yap\u0131s\u0131&nbsp;ve&nbsp;dinami\u011fi&nbsp;ile ilgili ilk biyoinformatik &ccedil;al\u0131\u015fmas\u0131 olmas\u0131, &Ccedil;ukurova &Uuml;niversitesinde y&uuml;r&uuml;t&uuml;len ilk &quot;Molek&uuml;ler Docking&quot; ve &quot;Molek&uuml;ler Dinamik&quot; &ccedil;al\u0131\u015fmas\u0131 olmas\u0131&rdquo; \u015feklinde s\u0131ralad\u0131.<\/span><\/span><\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>&Ccedil;ukurova &Uuml;niversitesi (&Ccedil;&Uuml;) Fen-Edebiyat Fak&uuml;ltesi Biyoloji B&ouml;l&uuml;m&uuml;, Kilis 7 Aral\u0131k &Uuml;niversitesi Molek&uuml;ler Biyoloji ve Genetik B&ouml;l&uuml;m&uuml;, Afyon Sa\u011fl\u0131k Bilimleri &Uuml;niversitesi Eczac\u0131l\u0131k Fak&uuml;ltesi ve Universidade Federal do Rio Grande do Sul &Uuml;niversitesi Fizikokimya B&ouml;l&uuml;m&uuml; ile i\u015fbirli\u011fi i&ccedil;erisinde y&uuml;r&uuml;t&uuml;len koronavir&uuml;se kar\u015f\u0131 in silico ila&ccedil; tarama &ccedil;al\u0131\u015fmas\u0131 \u0130ngiltere merkezli &quot;Journal of Biomolecular Structure and Dynamics&quot; adl\u0131 bilimsel dergide &hellip;<\/p>\n","protected":false},"author":1,"featured_media":4056,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[55],"tags":[5822,6745,4283,6746,2003],"class_list":["post-4055","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-universite","tag-calisma","tag-koronavirus","tag-sonuclandi","tag-tedavisine","tag-yonelik"],"amp_enabled":true,"_links":{"self":[{"href":"https:\/\/adanaseshaber.com.tr\/index.php?rest_route=\/wp\/v2\/posts\/4055","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/adanaseshaber.com.tr\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/adanaseshaber.com.tr\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/adanaseshaber.com.tr\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/adanaseshaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=4055"}],"version-history":[{"count":0,"href":"https:\/\/adanaseshaber.com.tr\/index.php?rest_route=\/wp\/v2\/posts\/4055\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/adanaseshaber.com.tr\/index.php?rest_route=\/wp\/v2\/media\/4056"}],"wp:attachment":[{"href":"https:\/\/adanaseshaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=4055"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/adanaseshaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=4055"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/adanaseshaber.com.tr\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=4055"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}